C. difficile should only be treated with metronidazole or vancomycin
ESCHAPPM are β-lactamase producing organisms. These are Enterobacter, Serratia, Citrobacter freundii, Hafnia, Acinetobacter/Aeromonas, Proteus (not mirabilis), Providencia & Morganella morganii
Not effective against Clostridium
Metronidazole is not effective against Peptostreptococcus
Teicoplanin is not effective against Enterococcus faecium
Gentamicin is not appropriate mono therapy for Staphylococcus aureus & should only be used in conjunction with a β-lactam
Due to increasing MIC, cefuxorime is not recommended therapy for Moraxella
Although it has other actions, ceftazidime should only be used for Pseudomonas
For simplicity, atypical organisms are not included above. Partial columns indicate incomplete coverage. ESBL-producing organisms are not susceptible to most antibiotics containing a beta-lactam ring; carbapenems are the usual agent of choice.
This chart does not replace local antibiotic preferences or ID expertise