1 vial

$4.95

  1. Induction of anaesthesia (particularly in the hypotensive patient)

IV:
20mg in 10ml vial
Inject undiluted by slow IV injection
Store at room temperature


ADULT DOSE

IV:
0.3mg/kg slow IV

PAEDIATRIC DOSE

IV:
0.3mg/kg slow IV

DOSAGE IN RENAL FAILURE AND RENAL REPLACEMENT THERAPY
Dose as in normal renal function

Etomidate is a hypnotic drug without analgesic activity. Intravenous injection of etomidate produces hypnosis characterised by a rapid onset of action, usually within 1 minute. Duration of hypnosis is dose dependent but relatively brief, usually 3-5 minutes when an average dose of 0.3 mg/kg is employed. Reduced cortisol plasma levels have been reported with induction doses of 0.3 mg/kg etomidate. These persist for approximately 6-8 hours and appear to be unresponsive to ACTH

CONTRAINDICATIONS

  1. Hypersensitivity to etomidate


WARNINGS
BECAUSE OF THE HAZARDS OF PROLONGED SUPPRESSION OF ENDOGENOUS CORTISOL AND ALDOSTERONE PRODUCTION, THIS FORMULATION SHOULD
NOT BE ADMINISTERED BY PROLONGED INFUSION.

PRECAUTIONS
General:
See WARNINGS

Laboratory Tests:
No tests additional to routine ICU tests are required

Drug/Laboratory Test Interactions:
None of note

Body as a Whole:
Anaphylaxis, adrenal suppression
Central Nervous System:
myoclonus
Cardiovascular System:
Hypertension, hypotension, tachycardia, bradycardia and other arrhythmias have occasionally been observed during induction and maintenance of anaesthesia
Respiratory System:
Hyperventilation, hypoventilation, apnea of short duration (5-90 seconds with spontaneous recovery), laryngospasm, hiccup and snoring suggestive of partial upper airway obstruction have been observed in some patients.
Gastrointestinal System:
Nausea and vomiting
Local:
Pain on injection