1 vial

$4.95

  • Induction of anaesthesia (particularly in the hypotensive patient)

IV:
20mg in 10ml vial
Inject undiluted by slow IV injection
Store at room temperature


ADULT DOSE

IV:
0.3mg/kg slow IV

PAEDIATRIC DOSE

IV:
0.3mg/kg slow IV

DOSAGE IN RENAL FAILURE AND RENAL REPLACEMENT THERAPY
Dose as in normal renal function

Etomidate is a hypnotic drug without analgesic activity. Intravenous injection of etomidate produces hypnosis characterised by a rapid onset of action, usually within 1 minute. Duration of hypnosis is dose dependent but relatively brief, usually 3-5 minutes when an average dose of 0.3 mg/kg is employed. Reduced cortisol plasma levels have been reported with induction doses of 0.3 mg/kg etomidate. These persist for approximately 6-8 hours and appear to be unresponsive to ACTH

CONTRAINDICATIONS

  • Hypersensitivity to etomidate


WARNINGS
BECAUSE OF THE HAZARDS OF PROLONGED SUPPRESSION OF ENDOGENOUS CORTISOL AND ALDOSTERONE PRODUCTION, THIS FORMULATION SHOULD
NOT BE ADMINISTERED BY PROLONGED INFUSION.

PRECAUTIONS
General:
See WARNINGS

Laboratory Tests:
No tests additional to routine ICU tests are required

Drug/Laboratory Test Interactions:
None of note

Body as a Whole:
Anaphylaxis, adrenal suppression
Central Nervous System:
myoclonus
Cardiovascular System:
Hypertension, hypotension, tachycardia, bradycardia and other arrhythmias have occasionally been observed during induction and maintenance of anaesthesia
Respiratory System:
Hyperventilation, hypoventilation, apnea of short duration (5-90 seconds with spontaneous recovery), laryngospasm, hiccup and snoring suggestive of partial upper airway obstruction have been observed in some patients.
Gastrointestinal System:
Nausea and vomiting
Local:
Pain on injection

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