1 tablet

5 cents

Calci-Tab, Caltrate, Calcium-Sandoz

  • Calcium supplementation

PO:
Calci-Tab 500 (500mg elemental calcium), Calci-Tab 600 (600mg elemental calcium), Caltrate tablets (600mg elemental calcium), Calci-Tab Effervescent (1gm elemental calcium), Calcium Sandoz (5.23gm of calcium lactate-gluconate, 0.8gm of calcium carbonate)


ADULT DOSE
PO:
500mg-1800mg of elemental calcium per day

PAEDIATRIC DOSE
Not applicable

DOSAGE IN RENAL FAILURE AND RENAL REPLACEMENT THERAPY
Dose as in normal renal function

CONTRAINDICATIONS:

  • Hypercalcaemia,

  • Digitalis toxicity.

  • Hyperphosphataemia (do not administer calcium if the Calcium + Phosphate is >5.5; this is an indication for dialysis)


WARNINGS
Nil

PRECAUTIONS
General
Elderly, fluid restriction, decreased GI motility, GI obstruction, dehydration.

Laboratory Tests:
No tests in addition to standard ICU tests are required.

Drug/Laboratory Test Interactions:
False Increase:
Chloride, benzodiazepine (false positive).
False Decrease:
Magnesium, lipase.

Calcium channel blockers:
Calcium administration may inhibit calcium channel blocker activity.
Doxycycline, tetracycline:
Co-therapy with a tetracycline and calcium carbonate can reduce the serum concentrations and efficacy of tetracyclines.
Quinolones:
Reduced bioavailability of quinolone antibiotics.
Thiazides:
Large doses of calcium with thiazides may lead to milk-alkali syndrome.

Cardiovascular:
Bradycardia, cardiac arrest, dysrhythmias, heart block, haemorrhage, hypotension, rebound hypertension, shortened QT interval.
Gastrointestinal:
Anorexia, constipation, diarrhoea, flatulence, nausea, obstruction, rebound hyperacidity, vomiting.
Genitourinary:
Renal dysfunction, renal failure, renal stones.
Metabolic:
Hypercalcaemia (drowsiness, lethargy, muscle weakness, headache, constipation, coma, anorexia, nausea, vomiting, polyuria, thirst); metabolic alkalosis; milk-alkali syndrome (nausea, vomiting, disorientation, headache).

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